Mumbai, April 23 -- The key domestic indices traded with significant losses in early trade as investor sentiment remained cautious amid uncertainty over the reopening of the Strait of Hormuz and a sharp surge in crude oil prices above the $100-per-barrel mark. Investors are also closely monitoring Q4 earnings for further cues. Market can be volatile amid NSE's weekly derivatives contract expiry. The Nifty traded near the 24,200 level.

Barring Pharma all the sectoral indices on the NSE were traded in red with consumer durables, auto and private bank shares declining the most.

At 09:25 IST, the barometer index, the S&P BSE Sensex declined 601.78 points or 0.76% to 77,912.47. The Nifty 50 index fell 177.25 points or 0.72% to 24,202.90.

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