Dhaka, May 5 -- Within the expanding conceptual landscape of endogenous peptides, LL-37 occupies a uniquely complex position. Traditionally framed as an antimicrobial cathelicidin-derived peptide, LL-37 has increasingly been reconsidered as a broader informational molecule embedded within the organism's innate regulatory architecture. Rather than operating solely as a terminal defence agent, contemporary research suggests that LL-37 may participate in a network of signalling interactions that influence immune calibration, tissue communication, redox balance, and inflammatory pattern recognition across diverse research domains.

Molecular Origin and Structural Characteristics

LL-37 is derived from the C-terminal region of the cathelicidin...