Washington DC, June 19 -- A newly discovered molecule, OLE, restored the brain's immune cells to a more protective state in Alzheimer's disease models. The treatment reduced the accumulation of toxic plaques and improved memory performance, highlighting its potential as a promising new therapeutic strategy.

Researchers in Spain and Switzerland have identified an experimental molecule that may help restore the brain's natural defences against Alzheimer's disease. The compound, known as OLE, appears to "reprogram" microglia, the brain's immune cells, allowing them to regain some of their protective abilities.

The research was led by Jose Vicente Sanchez Mut of the Institute for Neurosciences (IN), a joint center of the Spanish National Re...