Singapore Clinical Trial: A Phase 2, Randomized, Open-Label Study of VVD-133214 in Combination with Pembrolizumab compared with Pembrolizumab monotherapy in participants with advanced colorectal adenocarcinoma (CRC) harboring microsatellite instability (MSI) and/or deficient mismatch repair (DMMR)

Singapore, Nov. 5 -- The Health Sciences Authority received information related to the study titled 'A Phase 2, Randomized, Open-Label Study of VVD-133214 in Combination with Pembrolizumab compared wi... Read More

Singapore Clinical Trial: A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherapy (modified FOLFIRINOX or Gemcitabine plus Nab-paclitaxel) with or without Zoldonrasib (RMC 9805) as First-line Treatment in Patients with Metastatic KRAS G12D-mutated Pancreatic Adenocarcinoma (RASolute 305)

Singapore, Nov. 5 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Double-blind, Placebo-controlled Study of Investigator Choice of Chemotherap... Read More

Singapore Clinical Trial: A Phase 1, Investigator- and Participant-Blinded, Placebo-Controlled, Randomized, Multiple-Dose Study to Evaluate the Gastric Emptying Delay, Pharmacokinetics, Safety, and Tolerability of Eloralintide in Participants with Obesity or Overweight

Singapore, Nov. 5 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Investigator- and Participant-Blinded, Placebo-Controlled, Randomized, Multiple-Dose Stu... Read More

Singapore Clinical Trial: A Phase 1 randomized, double-blind, placebo-controlled, single-ascending-dose study investigating the safety and tolerability of ARD001 in healthy adult subjects and a Phase 2 open-label, multiple-dose study in adult subjects with hemophilia A

Singapore, Nov. 5 -- The Health Sciences Authority received information related to the study titled 'A Phase 1 randomized, double-blind, placebo-controlled, single-ascending-dose study investigating t... Read More

Singapore Clinical Trial: A Multinational, Multicenter Study With an Open-Label Phase 1b and a Randomized, Double-Blind, Placebo-Controlled Phase 3 Followed by an Open-Label Extension to Assess the Efficacy, Safety, Tolerability, and Pharmacokinetics of Radiprodil in Participants With GRIN-Related Neurodevelopmental Disorder

Singapore, Nov. 5 -- The Health Sciences Authority received information related to the study titled 'A Multinational, Multicenter Study With an Open-Label Phase 1b and a Randomized, Double-Blind, Plac... Read More

Clinical Trial: Generative AI-Based Evaluation of Clinical Thinking and Decision-Making in Medical Students

U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07915622) titled 'Generative AI-Based Evaluation of Clinical Thinking and Decision-Making in Medical Students'... Read More

Clinical Trial: Platelet Transfusion Thresholds in Non-Bleeding Patients

U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07915284) titled 'Platelet Transfusion Thresholds in Non-Bleeding Patients' on Oct. 18. Brief Summary: This i... Read More

Clinical Trial: Effect of the 4-7-8 Breathing Technique Before Central Venous Catheter Insertion

U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07917585) titled 'Effect of the 4-7-8 Breathing Technique Before Central Venous Catheter Insertion' on Oct. 26... Read More

Clinical Trial: Computer-Assisted Vocabulary Intervention for Spanish-English Bilingual Children With Developmental Language Disorder

U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07915115) titled 'Computer-Assisted Vocabulary Intervention for Spanish-English Bilingual Children With Develo... Read More

Clinical Trial: A Nurse-Led Digital Coaching Program to Improve Blood Sugar Control in Adults With Type 2 Diabetes

U.S., Nov. 5 -- ClinicalTrials.gov registry received information related to the study (NCT07916584) titled 'A Nurse-Led Digital Coaching Program to Improve Blood Sugar Control in Adults With Type 2 Di... Read More

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