Singapore Clinical Trial: A multi-center, open-label, phase I/II study to evaluate the safety and efficacy of asciminib with chemotherapy followed by asciminib plus blinatumomab in pediatric, adolescent, and young adult participants with relapsed or refractory BCR::ABL1-positive (Philadelphia positive, Ph+) or BCR::ABL1-like (Ph-like) acute lymphoblastic leukemia (ALL)

Singapore, Sept. 23 -- The Health Sciences Authority received information related to the study titled 'A multi-center, open-label, phase I/II study to evaluate the safety and efficacy of asciminib wit... Read More

Singapore Clinical Trial: A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy versus placebo with chemotherapy in patients with previously untreated locally recurrent inoperable or metastatic TNBC determined ineligible for PD(L)1 therapy based on PD-L1 negative disease

Singapore, Sept. 23 -- The Health Sciences Authority received information related to the study titled 'A Phase III, multisite, randomized, double-blind trial of BNT327 in combination with chemotherapy... Read More

Singapore Clinical Trial: CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitaxel and Gemcitabine versus Placebo in Combination with Nab-paclitaxel and Gemcitabine in Participants with Untreated Metastatic Pancreatic Ductal Adenocarcinoma Harboring Homozygous MTAP Deletion

Singapore, Sept. 23 -- The Health Sciences Authority received information related to the study titled 'CA2400030: A Randomized, Phase 2/3 Study Comparing Navlimetostat in Combination with Nab-paclitax... Read More

Singapore Clinical Trial: A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Phase 3 Study of Zipalertinib Plus Adjuvant Chemotherapy Versus Placebo Plus Adjuvant Chemotherapy in Stage IB-IIIA NSCLC Patients with Uncommon EGFR Mutations Following Complete Tumor Resection (REZILIENT4)

Singapore, Sept. 23 -- The Health Sciences Authority received information related to the study titled 'A Randomized, Placebo-Controlled, Double-Blind, Multi-Center Phase 3 Study of Zipalertinib Plus A... Read More

Singapore Clinical Trial: Beamion LUNG-3: A randomized, controlled, multi-center trial evaluating zongertinib as an adjuvant monotherapy compared with standard of care in patients with early-stage, resectable non-small cell lung cancer (Stage II-IIIB) harboring tyrosine kinase domain activating HER2 mutations

Singapore, Sept. 23 -- The Health Sciences Authority received information related to the study titled 'Beamion LUNG-3: A randomized, controlled, multi-center trial evaluating zongertinib as an adjuvan... Read More

Clinical Trial: Direct Pulp Capping With Biodentine in Permanent Teeth With Reversible Pulpitis

U.S., Sept. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07834424) titled 'Direct Pulp Capping With Biodentine in Permanent Teeth With Reversible Pulpitis' on Sept. ... Read More

Clinical Trial: Ischemic Compression and Low-Level Laser Therapy for Myofascial Low Back Pain

U.S., Sept. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07832422) titled 'Ischemic Compression and Low-Level Laser Therapy for Myofascial Low Back Pain' on Sept. 16... Read More

Clinical Trial: Chinese Multicenter Cohort Study of Intracerebral Hemorrhage

U.S., Sept. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07833410) titled 'Chinese Multicenter Cohort Study of Intracerebral Hemorrhage' on Sept. 14. Brief Summary:... Read More

Clinical Trial: Image-Guided Intra-Articular Versus Periarticular Injection in Sacroiliac Joint Pain

U.S., Sept. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07832864) titled 'Image-Guided Intra-Articular Versus Periarticular Injection in Sacroiliac Joint Pain' on S... Read More

Clinical Trial: Metabolomics and Transcriptomics of Low- and High-Grade Gliomas

U.S., Sept. 23 -- ClinicalTrials.gov registry received information related to the study (NCT07832734) titled 'Metabolomics and Transcriptomics of Low- and High-Grade Gliomas' on Sept. 09. Brief Summa... Read More

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