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Singapore Clinical Trial: A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab Tirumotecan, MK-2870) Followed by Carboplatin/Paclitaxel vs Chemotherapy, Both in Combination With Pembrolizumab as Neoadjuvant Therapy for High-Risk, Early-Stage, Triple-Negative Breast Cancer or Hormone Receptor-low Positive/Human Epidermal Growth Factor Receptor-2 Negative Breast Cancer

Singapore, July 21 -- The Health Sciences Authority received information related to the study titled 'A Phase 3 Randomized, Open-label Study to Evaluate the Efficacy and Safety of sac-TMT (Sacituzumab... Read More


Singapore Clinical Trial: A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig Plus Abiraterone Versus Investigator’s Choice in Participants with Chemotherapy-naïve Metastatic Castration-resistant Prostate Cancer

Singapore, July 21 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Open-label, Multicenter, Randomized Study of Xaluritamig Plus Abiraterone Versus Invest... Read More


Singapore Clinical Trial: Regime for vitamin D maintEnanCe In poSt-operatIVE patients (D-ECISIVE) Randomized Controlled Trial

Singapore, July 21 -- The Health Sciences Authority received information related to the study titled 'Regime for vitamin D maintEnanCe In poSt-operatIVE patients (D-ECISIVE) Randomized Controlled Tria... Read More


Singapore Clinical Trial: A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety of Firmonertinib Compared with Investigator’s Choice of Osimertinib or Afatinib as First-Line Treatment in Participants Who Have Locally Advanced or Metastatic Non-Small-Cell Lung Cancer with Epidermal Growth Factor Receptor P-Loop and Alpha C-Helix Compressing (PACC) Uncommon Mutations (ALPACCA)

Singapore, July 21 -- The Health Sciences Authority received information related to the study titled 'A Global, Phase 3, Randomized, Multicenter, Open-Label Study to Evaluate the Efficacy and Safety o... Read More


Singapore Clinical Trial: The effect of two icodextrin exchanges on fluid status and blood pressure control in children on chronic peritoneal dialysis

Singapore, July 21 -- The Health Sciences Authority received information related to the study titled 'The effect of two icodextrin exchanges on fluid status and blood pressure control in children on c... Read More


Singapore Clinical Trial: A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Efficacy and Safety of MK-2214 in Participants with Early Alzheimer's Disease

Singapore, July 21 -- The Health Sciences Authority received information related to the study titled 'A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Effic... Read More


Clinical Trial: COMPARISON OF LUNG RECRUITABILITY ASSESSMENT BY HYSTERESIS RATIO AND RECRUITMENT-TO-INFLATION RATIO, AND PEEP TITRATION IN ARDS.

U.S., July 21 -- ClinicalTrials.gov registry received information related to the study (NCT07713420) titled 'COMPARISON OF LUNG RECRUITABILITY ASSESSMENT BY HYSTERESIS RATIO AND RECRUITMENT-TO-INFLATI... Read More


Clinical Trial: Pre-procedural Risk Score-Based Endoscopist Assignment for Pain Reduction in Unsedated Colonoscopy

U.S., July 21 -- ClinicalTrials.gov registry received information related to the study (NCT07713953) titled 'Pre-procedural Risk Score-Based Endoscopist Assignment for Pain Reduction in Unsedated Colo... Read More


Clinical Trial: EUS-Guided ATI and SWE in Individuals With Normal FibroScan

U.S., July 21 -- ClinicalTrials.gov registry received information related to the study (NCT07714941) titled 'EUS-Guided ATI and SWE in Individuals With Normal FibroScan' on July 15. Brief Summary: Th... Read More


Clinical Trial: Combining Transcranial Magnetic Stimulation With Emotion Regulation Skills Training in Borderline Personality Disorder

U.S., July 21 -- ClinicalTrials.gov registry received information related to the study (NCT07714005) titled 'Combining Transcranial Magnetic Stimulation With Emotion Regulation Skills Training in Bord... Read More