Singapore Clinical Trial: A multicentre, randomised, double-blind, parallel group, placebo-controlled trial to assess the effects of oral TRPC6 inhibitor BI 764198 taken over a 104 week treatment period in adult and adolescent participants with primary focal segmental glomerulosclerosis (pFSGS) or genetic FSGS related to TRPC6 gene variants

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'A multicentre, randomised, double-blind, parallel group, placebo-controlled trial to assess the effe... Read More

Singapore Clinical Trial: A Phase 2b/Phase 3, randomized, double-blind, placebo-controlled, multicenter study, to investigate the efficacy and safety of lunsekimig in adult participants with inadequately controlled chronic obstructive pulmonary disease (COPD) characterized by an eosinophilic phenotype

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'A Phase 2b/Phase 3, randomized, double-blind, placebo-controlled, multicenter study, to investigate ... Read More

Singapore Clinical Trial: A Phase 1, Randomized, Placebo-Controlled, Single Ascending Dose-Escalation Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of LY4167586 in Participants with Obesity or Overweight who are Otherwise Healthy.

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'A Phase 1, Randomized, Placebo-Controlled, Single Ascending Dose-Escalation Study to Investigate the... Read More

Singapore Clinical Trial: A Phase 1/2, Randomized, Double-Masked, Placebo-Controlled, Multicenter Study to Assess the Safety, Pharmacokinetics, and Efficacy of AMG 732 in Healthy Subjects and Subjects with Moderate-to-Severe Active Thyroid Eye Disease

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'A Phase 1/2, Randomized, Double-Masked, Placebo-Controlled, Multicenter Study to Assess the Safety, ... Read More

Singapore Clinical Trial: Immunogenicity of Recombinant Zoster Vaccine in Long-term Solid Organ Transplant Recipients

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'Immunogenicity of Recombinant Zoster Vaccine in Long-term Solid Organ Transplant Recipients'. The fo... Read More

Singapore Clinical Trial: A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of MK-1084, Cetuximab, and mFOLFOX6 versus mFOLFOX6 With or Without Bevacizumab as First-line Treatment of Participants With KRAS G12C-mutant, Locally Advanced Unresectable or Metastatic Colorectal Cancer (KANDLELIT-012)

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Randomized, Open-label, Multicenter Clinical Study to Evaluate the Safety and Efficacy of... Read More

Singapore Clinical Trial: Phase 3 Study of the Efficacy and Safety of ION582 in Children and Adults with Angelman Syndrome

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'Phase 3 Study of the Efficacy and Safety of ION582 in Children and Adults with Angelman Syndrome'. T... Read More

Singapore Clinical Trial: A Phase 3, Open-Label, Multicenter, Extension Study of Acoramidis in Patients with Newly Diagnosed Variant Transthyretin Amyloid Cardiomyopathy (ACT-EARLY OLE)

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'A Phase 3, Open-Label, Multicenter, Extension Study of Acoramidis in Patients with Newly Diagnosed V... Read More

Singapore Clinical Trial: Healthy longevity with rapamycin (LONGER)

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'Healthy longevity with rapamycin (LONGER)'. The following are the other relevant details related to ... Read More

Singapore Clinical Trial: FaR-RMS: An overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma

Singapore, May 9 -- The Health Sciences Authority received information related to the study titled 'FaR-RMS: An overarching study for children and adults with Frontline and Relapsed RhabdoMyoSarcoma'.... Read More

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