Mumbai, March 11 -- The domestic equity indices ended with significant losses on Monday, snapping a two-day rising streak. The Nifty settled below the 22,350 mark after hitting the day's high of 22,526.60 in early trade. Healthcare and pharma stocks were in demand while media, PSU bank and metal shares witnessed selling pressure.

As per provisional closing data, the barometer index, the S&P BSE Sensex tumbled 616.75 points or 0.83% to 73,502.64. The Nifty 50 index fell 160.90 points or 0.72% to 22,332.65.

In the broader market, the S&P BSE Mid-Cap index shed 0.24% and the S&P BSE Small-Cap index slipped 2.01%.

Sellers outnumbered buyers. On the BSE, 924 shares rose and 3,039 shares fell. A total of 119 shares were unchanged.

The NSE's...