U.S., May 7 -- ClinicalTrials.gov registry received information related to the study (NCT06402617) titled 'Ablation of Focal Activation in Atrial Fibrillation' on April 29.
Brief Summary: Recurrent focal electrical activation (or ectopy) superseding sinus activation is the only mechanism proven to drive paroxysmal atrial fibrillation (AF). However, it has not been possible to show similar focal drivers during AF, owing to the limitations of mapping in persistent AF. RETRO-Mapping has been developed as a method to generate activation maps during AF to test the hypothesis that persistent AF is also maintained by focal drivers.
RETRO-Mapping is able to locate sites of focal activation that were isolated, intermittent, or recurrent during per...