U.S., Feb. 14 -- ClinicalTrials.gov registry received information related to the study (NCT06259500) titled 'Patient-derived Stem Cell Models of Anorexia Nervosa' on Feb. 6.
Brief Summary: Experimental and genetic data, as well as brain imaging, support a role for the hypothalamic Arcuate nucleus neurons and their communication with surrounding microglia in anorectic conditions, but it has until recently not been possible to explore these cells at a molecular level in anorexi nervosa (AN) patients. This attributed to the obvious lack of valid tissue and non-invasive imaging techniques of high enough resolution. Stem cell models have evolved as a useful tool for the exploration of other neuropsychiatric disorders with a comparably high gene...