Clinical Trial: A Study of Auxora in Patients With AKI and Injurious Lung "Crosstalk"

U.S., April 19 -- ClinicalTrials.gov registry received information related to the study (NCT06374797) titled 'A Study of Auxora in Patients With AKI and Injurious Lung "Crosstalk"' on April 16.

Brief Summary: Approximately 150 patients with acute kidney injury (AKI) associated with acute hypoxemic respiratory failure (AHRF) will be randomized at up to 40 sites. Patients will be randomly assigned to either Auxora or matching placebo. Study drug infusions will occur every 24 hours for five consecutive days for a total of five infusions.

Study Type: Interventional

Condition: Acute Kidney Injury

Intervention: * Drug: Auxora

1.25 mL/kg (2.0 mg/kg of zegocractin) intravenously (IV) over 4 hours at 0 hours, and then 1.0 mL/kg (1.6 mg/kg of ze...